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USA remote

Study Manager, Toxicology

Revolution MedicinesRemote (United States)Posted 1 Sept 2026

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About this role

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients. The Opportunity: The preclinical study manager is responsible for the operational activities associated with performing non-GLP and GLP toxicology studies from research to late phases of clinical development. This includes being the primary operational contact and representative for RevMed to the contract research organization (CRO) performing each study.

He/she will be responsible for ensuring that each study’s scientific and corporate objectives are achieved, and are compliant with appropriate regulations, policies, standard operating procedures, and all relevant international regulatory guidelines/regulations. Timely resolution of study-related issues, liaising with internal experts and/or consultants, and informing appropriate personnel are pivotal to being successful in this role.

Required Skills, Experience and Education: Work with Contract Research Organizations (CROs), internal subject matter experts, and toxicologists to help design protocols that achieve the scientific objectives of each study. Monitor non-GLP and GLP toxicology studies through effectively managing day-to-day study-related activities and ensure study objectives are met against project goals. Assist toxicologists in the review of protocols, study reports, and protocol/report amendments to ensure high-quality results are generated by CROs.

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Coordinate study-related activities between RevMed personnel (toxicologists, Project Management, CMC, Bioanalytical, Regulatory, Finance, and Legal groups), and CROs to ensure program needs and timelines are met. Assist with data analysis and generate results tables and graphs as needed. Participate in regulatory submissions (e.g. preparation and/or review applicable nonclinical sections of IBs, NDAs, BLAs, etc.). Develop and maintain relationships with study directors, principal investigators, and external collaborators.

Work with QA to facilitate CRO vendor selection/audit and due diligence activities. Negotiate contracts and manage internal approvals & execution process. Support the development and/or review of SOPs, policies, and guidelines. Other duties will be assigned as needed. Preferred Skills: BS degree in science and minimum 5+ years of relevant experience in biotech, pharmaceutical and/or CRO industries. Knowledge of current GLP regulations, and ICH and FDA guidelines for drug development.

Strong interpersonal skills and ability to work with cross-functional project teams and CROs. Effective communication, both verbally and in writing, and ability to facilitate open cross-functional collaboration. Ability to prioritize responsibilities and meet deadlines. Self-motivated and independent work ethics. Ability to travel to CRO partners as needed. #LI-Remote #LI-CT1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below.

The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please contact [email protected] . Base Pay Salary Range $143,000 — $178,000 USD We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines.

These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.

If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.

Source listing: greenhouse_revolutionmedicines

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