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Senior Manager of DevOps (Data Science Production Engineering)

NateraUS RemotePosted 4 Sept 2026

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About this role

This is an exciting opportunity to lead a DevOps team at Natera, a global leader in precision medicine and genomics testing. As a Senior Manager of the DevOps team inside our Data Science Production Engineering (DSPE) department, you will have the opportunity to work with Natera's diverse and ultra-large data sets (up to PB size), build upon the latest information and cloud technologies, create solutions for the most cutting-edge medical diagnostics and genomics applications, and make real impact by delivering reliable, efficient, high performance data/cloud/automation systems to support Natera's Lab Operations and Genetic Counselor/Lab Director teams, and ultimately impact patients' medical outcomes.

PRIMARY RESPONSIBILITIES: Leadership Lead a DevOps team, working closely with other DSPE teams, to develop, test, deploy, maintain, and update DSPE's data platforms, cloud platforms, automation systems, and analytics systems Manage the DevOps team, to achieve the timely and efficient delivery of software products and systems with correct and robust functionality. Train and coach team members on new technologies, procedures, and guidelines/best practices.

Create and maintain operational visibility (e.g., workload, productivity, etc.) of the DSPE DevOps team. Technical Translate DSPE's business needs and project requirements into technical specifications and implementation plans. Working with DSPE leadership teams, create suitable system architecture and infrastructure design documents that can be efficiently implemented and maintained. Maintain and optimize infrastructure performance, monitoring key system metrics including network I/O, disk I/O, memory allocation, and compute resource utilization.

Contribute to key development, testing, deployment, validation, maintenance, and update activities. Quality, Compliance, and Documentation Improve and enforce procedures for work efficiency, quality, and compliance. Lead and manage the technical documentation's creation and maintenance/update for all DSPE DevOps owned software tools and systems, for example, design specifications, software verification and validation (V&V) protocols and reports, deployment/update/maintenance records, user guides, etc.

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Create training materials, and contribute to training activities, on DSPE DevOps owned software tools and systems. Cross-Functional Engage proactively and directly with engineering and operational stakeholders to align infrastructure roadmaps, resolve technical dependencies, and report platform performance metrics. Represent the DSPE DevOps team in stakeholder meetings. QUALIFICATIONS: Minimal Bachelor's Degree in Computer Science, Software Engineering, Bioinformatics, or a related field.

Advanced degrees preferred. Minimal 10 years of relevant industry experience for candidates with only a Bachelor's Degree. Minimal 8 years of relevant industry experience for candidates with a Master's Degree. Minimal 4 years of relevant industry experience for candidates with a Doctorate degree. Minimal 3 years of working experience in a highly regulated environment, e.g., CLIA and/or FDA compliant settings. Minimal 3 years of management experience leading a DevOps team, or a software development team.

Demonstrable experience in designing, delivering, and maintaining/updating custom-developed software tools or systems for production environments, preferable in high-throughput settings (e.g., heavy traffic and/or high computation load). Demonstrable experience in creating software design specification documents, verification and validation documents, and user manuals. KNOWLEDGE, SKILLS, AND ABILITIES: Excellent Python programming skills, with substantial cloud application and/or automation system development experience.

Proficient with RDBMS systems such as PostgreSQL and/or MySQL, and substantial working experience in for-production database-based application development. Working knowledge in optimizing system architecture and individual components for performance, scalability, and/or reliability. Proficiency in tool/system performance evaluation methods, and in-depth understanding of key factors, such as RAM, Disk IO, Network IO's impact on system/tool's performance.

Proficiency with AWS, and substantial working experience in developing for-production software tools/systems using AWS services. Proficiency in SDLC and software development and testing methodologies. Proficient Linux command line skills, and past Linux application development experience. Past experience and working knowledge in genomics and bioinformatics technologies. Good understanding and past working experience with genomics data, such as FASTQ, BAM, VCF files.

Proficiency in Git workflow and version control systems like GitHub and/or GitLab. Past experience in developing automation solutions. Preferred but not required: IaC skills and experiences, such as CloudFormation, Terraform, and/or Ansible. Good documentation practices and coding style. Strong verbal and written communication skills. Strong interpersonal skills. Strong integrity. Team player. The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location.

This may differ in other locations due to cost of labor considerations. Remote USA $151,000 — $188,700 USD OUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! For more information, visit www.natera.com .

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status.

We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents. Link: https://www.natera.com/notice-of-data-collection-california-residents/ Please be advised that Natera will reach out to candidates with a @ natera.com &nbsp

Source listing: greenhouse_natera

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