Medical Director, Clinical Development

About this role

Would you enjoy leading drug development for rare conditions? Are you a medic with experience designing clinical trials and interacting with regulatory authorities? If so, now is your chance to join Ascendis Pharma as our new Medical Director, Clinical Development, Endocrine & Rare Diseases Ascendis Pharma is a global biopharmaceutical company committed to making a meaningful difference in patients’ lives. Guided by our core values of Patients, Science, and Passion, we are applying our innovative TransCon® technology platform to fulfill our mission of developing new therapies that demonstrate best-in-class potential to address unmet medical needs.

At our headquarters in Hellerup, Denmark, research facilities in Heidelberg, Germany, and additional offices across Europe and the United States, we are advancing programs in our Endocrinology Rare Disease and Oncology portfolios. We also collaborate with partners on the development of TransCon-based products in other therapeutic areas and markets. We are seeking an energetic and passionate Medical Director to join our team.

As a member of the Ascendis Pharma team, you will play a crucial role in driving the design, safety monitoring, and data analysis within the Endocrine and Rare Disease Medical Sciences area. This is an exciting opportunity to work in a fast-paced environment, collaborate with cross-functional, global teams working together to achieve extraordinary results. You will join the Clinical Development team, being part of the Endocrine & Rare Disease Medical Sciences organization.

You will report directly to the VP of Clinical Science who is based in the US. You will be based in Hellerup together with the Danish team. Since you will join a team based in different time zones, you must be available for evening meetings. This position also may require occasional international travel. Your key responsibilities will be Contribute to formulation and implementation of the Clinical Development Plan Leverage medical expertise and hands-on clinical experience to promote relevance and rigor of the development program For clinical trials: design, provide overall oversight, and support site and subject retention Serve as a Medical Monitor for clinical trials, ensure study integrity, and track accumulating safety and efficacy data Provide leadership to teams of medical monitors and study teams Ensure successful completion of trial-related documents (including clinical trial protocols, investigator brochures, medical monitoring plans, site training materials, clinical study reports, health authority responses, standard operating procedures, etc.) with cross-functional team members Ensure study integrity, and track accumulating safety and efficacy data Analyze, evaluate, interpret, and report clinical data Anticipate and solve complex drug development problems Contribute to regulatory strategy Contribute to drafting and reviewing of clinical documents, manuscripts, presentations, and regulatory submissions Maintain up-to-date knowledge of relevant science, medical information, good clinical practices, and regulatory guidance Collaborate with—and serve as a clinical research resource for—cross-functional colleagues (e.g.