Director, GxP Quality Governance and Partnerships

About this role

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients. The Opportunity: The Director, GxP Quality Governance & Partnerships will provide Quality leadership in establishing and managing Quality Agreements and related arrangements supporting Revolution Medicines’ expanding global development, manufacturing, and commercial operations.

The Director will lead the development, negotiation, implementation, and lifecycle management of Quality Agreements across a diverse network of external partners and internal entities. Working closely with Quality, Legal, Development, Manufacturing, Supply Chain, Strategic Sourcing, CMC Regulatory, and external partners, the role will establish clear responsibilities, appropriate oversight, and alignment with applicable regulatory requirements.

The position will also help build a scalable approach to Quality governance, including standardized agreement practices, defined accountability, effective communication, and oversight of agreed Quality commitments. As the organization grows, the role offers opportunities to contribute to broader external partner Quality management and compliance initiatives. This position reports to the Executive Director, GxP Quality and Compliance.

Responsibilities: Lead the development, review, negotiation, and execution of Quality Agreements and related Quality arrangements supporting clinical development and global commercial operations. Manage agreements involving CMOs, CDMOs, contract laboratories, packaging and distribution partners, clinical collaborations, other GxP service providers, and intra-company arrangements. Establish clear Quality responsibilities, decision-making authority, oversight expectations, and communication requirements across internal and external partnerships.